[Use of the prognosis markers in the treatment for the invasive cervical carcinoma].
نویسنده
چکیده
The uterine cervix invasive carcinoma represents a major public health problem, mainly in the developing countries. Its treatment, based on radical hysterectomy, radiotherapy and/or chemotherapy presents a considerable morbidity. Prognostic markers should be taken into consideration in the therapeutic planning, so that the results would be optimized, complications reduced, and patients' survival prolonged. Accepted prognostic markers are: stage, tumoral size, histological type, degree of differentiation, lymphovascular invasion, depth of the stromal invasion, presence of lymph nodal metastases, and surgical margins involvement. This study aims at making a literature review concerning the use of theses markers in the therapeutic planning of women with uterine cervix invasive carcinoma. The treatment based on these markers may present better results, with lower ratio of complications and an improvement in the patients' survival.
منابع مشابه
The Expression Of Biomarkers In Invasive Ductal Carcinoma Of Breast Through Tissue Array Method And Its Comparison With Clinicopathologic Features
Background and Objective: In this study, we explored expression rate, some biomarkers affecting the prognosis of the breast carcinoma, and the relationship between these markers and clinicopathologic features of the disease as well as the relationship between each of these markers through a tissue array technique. Materials and Methods: This study was an observational and cross-sectional st...
متن کاملCorrelation of P16 (Ink4a) and CK17 to HPV (16E6+18E6) in Premalignant and Malignant Lesions of Uterine Cervix: A Clinicopathologic Study
Background: This research was accomplished to evaluate the IHC expression of p16 (ink4a) and CK17 in low grade cervical intraepithelial lesions (LSIL), high grade cervical intraepithelial lesions (HSIL) and invasive cervical carcinomas and to assess their correlation to HPV (16E6+18E6). Methods: The study...
متن کاملبررسی ارتباط روشهای رایج پیشگیری از بارداری با سرطان مهاجم سرویکس
Background and Aim: Invasive cervical carcinoma is one of the most common malignancies in women. The risk factors are old age, low socioeconomic status, multiparity, first intercourse in low age, multipartner, history of infection and sexual transmitted disease (STD), smoking, long term use of oral contraceptive (OCP), malnutrition, and so on. There has been a possible relationship between inva...
متن کاملPrognostic molecular markers in hepatocellular carcinoma (Review article
Hepatocellular carcinoma (HCC) is the 5th commonest malignancy worldwide and is the third most common cause of cancer-related death. The prevalence is different in the world. The ability to predict patients at higher risk of recurrence and with a poor prognosis would help to guide surgical and chemotherapeutic treatment according to individual risk. As understanding of hepatocarcinogenesi...
متن کاملPure Mucinous Carcinoma of the Breast
Mucinous carcinoma of the breast is a well differentiated, rare histological type of invasive ductal carcinoma, seen in oldest median age (69 years). We describe a case of a 60 yr old female with large right breast mass of 10 years duration with no nodal involvement. The reasons to present this case are 1) Because of its rarity. 2) Despite having a large tumour size, the axillary lymph node ...
متن کاملبررسی ایمنوهیستوشیمی وضعیت گیرنده های استروژن و پروژسترون و نشانگر تکثیر سلولی (Ki-67) در سرطان پستان
Background and Aim: Breast carcinoma is a pervasive malignancy in the world, and in our country-Iran-as well. Extensive studies have been done on its diagnostic and therapeutic procedures and factors affecting its prognosis. The present study aimed at determining proliferative rate of cells, the condition of steroid hormone receptors, correlation of these with each other and with other factors ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia
دوره 31 9 شماره
صفحات -
تاریخ انتشار 2009